Remifentanil versus fentanyl compared in a target-controlled infusion of propofol anesthesia: quality of anesthesia and recovery profile
Identifieur interne : 000744 ( Main/Exploration ); précédent : 000743; suivant : 000745Remifentanil versus fentanyl compared in a target-controlled infusion of propofol anesthesia: quality of anesthesia and recovery profile
Auteurs : Demet Coskun [Turquie] ; Hulya Celebi [Turquie] ; Gozde Karaca [Turquie] ; Lale Karabiyik [Turquie]Source :
- Journal of Anesthesia [ 0913-8668 ] ; 2010.
English descriptors
- Teeft :
- Anaesthesia, Anesth, Anesth analg, Anesthesia, Anesthesiology, Anesthetic, Baseline value, Bispectral, Bispectral index, Clin anesth, Dos, Emergence, Emergence time, Extubation, Extubation time, Fentanyl, Fentanyl group, First minute, Infusion, Intravenous, Intubation, Opening time, Opioid, Orientation time, Outpatient, Pacu, Present study, Propofol, Propofol infusion, Recovery profile, Regimen, Remifentanil, Remifentanil group, Safe extubation, Septorhinoplasty operation, Significant difference, Tiva, Total intravenous anesthesia, Tracheal intubation.
Abstract
Abstract: Purpose: The aim of the present study was to compare the clinical properties of fentanyl versus remifentanil in a target-controlled infusion (TCI) of propofol anesthesia regimen with bispectral index (BIS) monitoring. Methods: Forty consenting patients scheduled for elective septorhinoplasty were prospectively studied as one of two groups: fentanyl (group F) or remifentanil (group R). After loading boluses of fentanyl 3 μg kg−1 or remifentanil 1 μg kg−1 were administered, the continuous infusion of fentanyl or remifentanil was started at a rate of 0.03 or 0.15 μg kg−1 min−1, respectively. Propofol infusion was then commenced with a 3 μg ml–1 effect site concentration (Ce) by means of a TCI device. The Ce propofol was adjusted to keep BIS at 50 ± 10. Results: The general mean value of propofol Ce for group F and group R was 4.0 and 3.5 μg ml−1, respectively. As to the recovery profile, the eye opening time (mean, 6.7 vs. 4.6 min), extubation time (mean, 7.3 vs. 4.7 min), and orientation time (mean, 7.6 vs. 4.9 min) were found to be significantly longer in group F than in group R. Conclusion: We concluded that in propofol-based TCI anesthesia under BIS supervision for septorhinoplasty operations, remifentanil was better than fentanyl, especially with respect to emergence from total intravenous anesthesia (TIVA). Furthermore, the durations of anesthesia and operation were rather short, which indicates that fentanyl can be safely used.
Url:
DOI: 10.1007/s00540-010-0898-1
Affiliations:
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sort="Coskun, Demet" uniqKey="Coskun D" first="Demet" last="Coskun">Demet Coskun</name><affiliation wicri:level="1"><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Anesthesiology and Reanimation, Gazi University Faculty of Medicine, 06500, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Turquie</country></affiliation></author><author><name sortKey="Celebi, Hulya" sort="Celebi, Hulya" uniqKey="Celebi H" first="Hulya" last="Celebi">Hulya Celebi</name><affiliation wicri:level="1"><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Anesthesiology and Reanimation, Gazi University Faculty of Medicine, 06500, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author><author><name sortKey="Karaca, Gozde" sort="Karaca, Gozde" uniqKey="Karaca G" first="Gozde" last="Karaca">Gozde Karaca</name><affiliation wicri:level="1"><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Anesthesiology and Reanimation, Gazi University Faculty of Medicine, 06500, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author><author><name sortKey="Karabiyik, Lale" sort="Karabiyik, Lale" uniqKey="Karabiyik L" first="Lale" last="Karabiyik">Lale Karabiyik</name><affiliation wicri:level="1"><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Anesthesiology and Reanimation, Gazi University Faculty of Medicine, 06500, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Anesthesia</title><title level="j" type="abbrev">J Anesth</title><idno type="ISSN">0913-8668</idno><idno type="eISSN">1438-8359</idno><imprint><publisher ref="https://scientific-publisher.data.istex.fr/ark:/67375/H02-SWLMH5L1-1">Springer Japan</publisher><pubPlace>Japan</pubPlace><date type="published" when="2010">2010</date><biblScope unit="vol" from="24" to="24">24</biblScope><biblScope unit="issue" from="3" to="3">3</biblScope><biblScope unit="page" from="373">373</biblScope><biblScope unit="page" to="379">379</biblScope></imprint><idno type="ISSN">0913-8668</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0913-8668</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Anaesthesia</term><term>Anesth</term><term>Anesth analg</term><term>Anesthesia</term><term>Anesthesiology</term><term>Anesthetic</term><term>Baseline value</term><term>Bispectral</term><term>Bispectral index</term><term>Clin anesth</term><term>Dos</term><term>Emergence</term><term>Emergence time</term><term>Extubation</term><term>Extubation time</term><term>Fentanyl</term><term>Fentanyl group</term><term>First minute</term><term>Infusion</term><term>Intravenous</term><term>Intubation</term><term>Opening time</term><term>Opioid</term><term>Orientation time</term><term>Outpatient</term><term>Pacu</term><term>Present study</term><term>Propofol</term><term>Propofol infusion</term><term>Recovery profile</term><term>Regimen</term><term>Remifentanil</term><term>Remifentanil group</term><term>Safe extubation</term><term>Septorhinoplasty operation</term><term>Significant difference</term><term>Tiva</term><term>Total intravenous anesthesia</term><term>Tracheal intubation</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Purpose: The aim of the present study was to compare the clinical properties of fentanyl versus remifentanil in a target-controlled infusion (TCI) of propofol anesthesia regimen with bispectral index (BIS) monitoring. Methods: Forty consenting patients scheduled for elective septorhinoplasty were prospectively studied as one of two groups: fentanyl (group F) or remifentanil (group R). After loading boluses of fentanyl 3 μg kg−1 or remifentanil 1 μg kg−1 were administered, the continuous infusion of fentanyl or remifentanil was started at a rate of 0.03 or 0.15 μg kg−1 min−1, respectively. Propofol infusion was then commenced with a 3 μg ml–1 effect site concentration (Ce) by means of a TCI device. The Ce propofol was adjusted to keep BIS at 50 ± 10. Results: The general mean value of propofol Ce for group F and group R was 4.0 and 3.5 μg ml−1, respectively. As to the recovery profile, the eye opening time (mean, 6.7 vs. 4.6 min), extubation time (mean, 7.3 vs. 4.7 min), and orientation time (mean, 7.6 vs. 4.9 min) were found to be significantly longer in group F than in group R. Conclusion: We concluded that in propofol-based TCI anesthesia under BIS supervision for septorhinoplasty operations, remifentanil was better than fentanyl, especially with respect to emergence from total intravenous anesthesia (TIVA). Furthermore, the durations of anesthesia and operation were rather short, which indicates that fentanyl can be safely used.</div></front></TEI><affiliations><list><country><li>Turquie</li></country></list><tree><country name="Turquie"><noRegion><name sortKey="Coskun, Demet" sort="Coskun, Demet" uniqKey="Coskun D" first="Demet" last="Coskun">Demet Coskun</name></noRegion><name sortKey="Celebi, Hulya" sort="Celebi, Hulya" uniqKey="Celebi H" first="Hulya" last="Celebi">Hulya Celebi</name><name sortKey="Coskun, Demet" sort="Coskun, Demet" uniqKey="Coskun D" first="Demet" last="Coskun">Demet Coskun</name><name sortKey="Karabiyik, Lale" sort="Karabiyik, Lale" uniqKey="Karabiyik L" first="Lale" last="Karabiyik">Lale Karabiyik</name><name sortKey="Karaca, Gozde" sort="Karaca, Gozde" uniqKey="Karaca G" first="Gozde" last="Karaca">Gozde Karaca</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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